Company: GMP Unit University Hospital & Paracelsus Medical University, Salzburg
Job title: Head, Department of Transfusion Medicine & Director
Eva Rohde is Head of the Department of Transfusion Medicine at the University Hospital of the Paracelsus Medical University in Salzburg, Austria. She received her M.D. from the Karl-Franzens University of Graz, Austria in 1994, finished training in Transfusion Medicine in 2005 and spent several years in stem cell research as a postdoctoral fellow. Her research focuses on the application of stem cell-based therapies with special emphasis on their extracellular vesicles (MSCEVs).
Eva Rohde is Founding Member of the Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TRECS), Austria and Director and Qualified Person of the SCI-TReCS GMP Unit. The GMP Unit in Salzburg has achieved the pharmaceutical manufacturing authorization for MSC and MSC-EVs in 2015 and participated a clinical trial testing MSCs in multiple sclerosis. Recent effort is directed towards the preclinical characterization and the regulatory requirements for the clinical assessment and future application of stem-cell based products, including stromal cell-derived extracellular vesicles (EVs). In vitro and in vivo potency assays to define the immunomodulatory, neuroprotective, neuroregenerative and scarless healing support of MSC-EVs are currently developed. In a named patient use experiment, a single treatment of the inner ear with MSC-EVs was performed together with partners from the medical school Hanover and resulted in a very good safety outcome over a period of more than 12 months. Recently, her work at the GMP Unit Salzburg was highlighted in an outlook article in Nature
Clinical Potential of Unmodified Mesenchymal Stromal Cell- Derived EV Therapeutics 3:00 pm
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day: Day One