8:00 am Morning Speed Networking

8:20 am Chair’s Opening Remarks

ENGINEERING CONSISTENT & EFFECTIVE EXOSOME BASED THERAPEUTICS

8:30 am Neural Exosomes as a Targeted Therapeutic & Drug Delivery System

• Steven Stice Co-Founder & Chief Scientific Officer & Professor, Aruna Bio

9:00 am Producing EVs at the Clinical Scale

• Chris Baldwin Chief Commercial Officer, Exopharm Ltd.

9:30 am Scalable Commercial Manufacturing – A Key Strategic Element for Success of the Next Generation of Exosome-Based Cell Free Therapies

• Davide Zocco Senior Manager, Lonza Pharma-Biotech

10:00 am Extracellular Vesicles: A Trojan Horse for Delivery of Therapeutic Gene Editing Modalities

• Koen Breyne Post-Doctoral Researcher, Massachusetts General Hospital, Harvard Medical School

10:30 am Virtual Speed Networking

11:00 am Hybridosomes, an Exosome-Based Platform for Targeted, Re- Dosable & Durable Gene Therapies

• Joel de Beer Managing Director, Anjarium Biosciences AG

11:30 am Applying an In Silico Platform to Engineer EVs as Delivery Vehicles

• Alex Mok Co-Founder & Chief Executive Officer, Mantra Bio

12:00 pm NanoFlow Cytometry and Multiple Scatters for EV Characterization in Therapeutics

• Alfonso Blanco Fernandez Associate Professor, UCD Conway Institute at University College Dublin - Beckman Coulter Sponsored Talk

12:30 pm Virtual Speed Networking

2:00 pm A Unique Strategy to Load Therapeutic Proteins into Exosomes

• Chulhee Choi Chief Executive Officer, ILIAS Biologics Inc.

ADVANCING EXOSOME THERAPEUTICS TO THE CLINIC

• Sophie Parmentier-Batteur Director, Neurodegenerative Diseases Discovery, Merck Research Laboratories

2:30 pm Tactically Preparing for Clinical Progression

• Shelley Hartman Chief Executive Officer, Aegle Therapeutics

3:00 pm “Good Things Come In Small Packages”: Application of Exosome- Based Therapeutics in Neonatal Cardio-Respiratory Disease

• Gareth Willis Instructor, Pediatrics, Boston Children’s Hospital, Harvard Medical School

3:30 pm Panel Discussion: Advancing Exosome Therapeutics to the Clinic

• Gareth Willis Instructor, Pediatrics, Boston Children’s Hospital, Harvard Medical School
• Steven Stice Co-Founder & Chief Scientific Officer & Professor, Aruna Bio
• Shelley Hartman Chief Executive Officer, Aegle Therapeutics

4:00 pm Chair’s Closing Remarks & End of Day One